Pharmacy Technician Certification Board (PTCB)

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Free Pharmacy Technician Certification Board (PTCB) Questions

1.

Which piece of legislation separated medication into two groups, OTC and Legend Drugs?

  • Pure Food and Drug Act
  • Controlled Substances Act
  • Durham-Humphrey Amendment
  • Kefauver-Harris Amendment

Explanation

Explanation
The Durham-Humphrey Amendment of 1951 formally separated medications into two categories: over-the-counter (OTC) and legend drugs (prescription-only). This legislation clarified which drugs require a physician’s authorization and which can be sold directly to consumers, creating a foundation for modern prescription regulation. The other acts address drug safety, manufacturing, or controlled substances but do not make this OTC/prescription distinction.
Correct Answer Is:
Durham-Humphrey Amendment
2.

A phlebotomist needs to collect a PT from a patient with a difficult vein. Which of the following is the best tube for the draw?

  • Light green
  • Lavender
  • Royal blue
  • Light blue

Explanation

Explanation
Prothrombin time (PT) tests require plasma collected in tubes containing sodium citrate, which preserves clotting factors. Light blue–top tubes contain sodium citrate and are specifically used for coagulation studies like PT and aPTT. Lavender tubes contain EDTA for hematology tests, light green tubes contain heparin for plasma chemistry, and royal blue tubes are used for trace element testing. Using the correct anticoagulant is critical for accurate PT results.
Correct Answer Is:
Light blue
3.

Which of the following are legal way(s) to receive a prescription for a schedule II drug barring an emergency? Select all that apply.

  • Phoned in
  • A written order
  • Electronically prescribed
  • Faxed in

Explanation

Explanation

For Schedule II drugs, the law is strict because of their high potential for abuse. Barring an emergency, the legal ways to receive a prescription include a written order or an electronically prescribed prescription via an approved e-prescribing system. Phoned-in prescriptions are only allowed in true emergencies, and faxes are generally used for certain situations (like long-term care or hospice), but the original written or electronic prescription is required for dispensing. These rules help prevent misuse and diversion of highly controlled medications.

Correct Answer Is:

A written order

Electronically prescribed


4.

What is a common side effect of HMG-CoA Reductase Inhibitors?

  • Drowsiness
  • GI Discomfort / Bleeding
  • Muscle Pain
  • Discoloration of Urine
  • Diarrhea

Explanation

Explanation
HMG-CoA Reductase Inhibitors, also known as statins, are used to lower cholesterol. A common side effect is muscle pain or myopathy, which can range from mild aches to severe muscle damage in rare cases. Patients are monitored for muscle-related symptoms during therapy. Other listed effects, such as GI bleeding or urine discoloration, are not typical of statins.
Correct Answer Is:
Muscle Pain
5.

Which Act shortened the required text for prescription medication bottles to read "Rx Only"?

  • FDA Modernization Act
  • OBRA
  • HIPAA
  • Hatch-Waxman Act

Explanation

Explanation
The FDA Modernization Act of 1997 simplified prescription labeling requirements, allowing medications to be labeled with “Rx Only” instead of longer, more detailed text. This change helped standardize prescription labels and make them easier to understand. OBRA focuses on patient counseling, HIPAA addresses privacy, and the Hatch-Waxman Act deals with generic drug market exclusivity.
Correct answer:
FDA Modernization Act
6.

Which of the following can be used to treat asthma?

  • Beta-agonists
  • ACE Inhibitors
  • HMG-CoA Reductase Inhibitors
  • Beta-Blockers

Explanation

Explanation
Beta-agonists are commonly used to treat asthma because they relax the smooth muscles of the airways, making it easier to breathe. Short-acting beta-agonists provide quick relief during asthma attacks, while long-acting forms help control chronic symptoms. ACE inhibitors are for blood pressure, HMG-CoA reductase inhibitors (statins) treat high cholesterol, and beta-blockers can actually worsen asthma by constricting airways in susceptible patients.
Correct Answer Is:
Beta-agonists
7.

C-II's may be transferred how many times?

  • 1
  • 0
  • Unlimited in 1 year
  • 5

Explanation

Explanation
Schedule II (C-II) controlled substances cannot be transferred between pharmacies. The law prohibits any transfer of these medications for refill purposes due to their high potential for abuse and dependency. Patients must obtain each C-II prescription directly from the original prescriber or pharmacy.
Correct Answer Is:
0
8.

Airflow on a Vertical Laminar Flow Hood can be described as:

  • From side to side
  • From top to bottom
  • From bottom to the top
  • From front to back

Explanation

Explanation
A vertical laminar flow hood directs sterile, HEPA-filtered air from the top of the hood downward in a unidirectional flow. This top-to-bottom airflow sweeps away contaminants from the work surface and the sterile materials being handled, minimizing the risk of microbial contamination. The controlled laminar flow is a critical feature in aseptic compounding, as it ensures a constant barrier of clean air over the sterile products, reflecting the precision and engineering of cleanroom design in pharmacy practice.
Correct Answer Is:
From top to bottom
9.

The list of medications that an insurance has agreed to pay for is known as:

  • Deductible
  • Formulary
  • Donut Hole
  • Copay

Explanation

Explanation
A formulary is an official list of prescription medications that a health insurance plan covers. It is designed to guide prescribers and patients in selecting medications that are safe, effective, and cost-efficient. Medications not on the formulary may require prior authorization or may not be covered at all. Understanding the formulary helps patients manage costs and ensures access to approved treatments. Other terms—deductible, copay, and donut hole—relate to out-of-pocket costs or coverage gaps, not the approved medication list itself.
Correct answer:
Formulary
10.

Mr. Madison would like to fill his prescription of benazepril. What class of drugs does his medication belong?

  • ACE inhibitor
  • Histamine H2 receptor antagonist
  • Histamine H1 receptor antagonist
  • Beta-blocker

Explanation

Explanation
Benazepril is an ACE inhibitor (Angiotensin-Converting Enzyme inhibitor), which is commonly used to treat high blood pressure and heart failure. ACE inhibitors work by relaxing blood vessels, reducing blood pressure, and decreasing the workload on the heart. H2 and H1 receptor antagonists are used for allergies and acid reflux, while beta-blockers also treat blood pressure but work via a different mechanism.
Correct Answer Is:
ACE inhibitor

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