ATI Anatomy and Physiology Exam

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Free ATI Anatomy and Physiology Exam Questions
Which of the following is a solution containing a salt concentration lower than the concentration in red blood cells
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Hypotonic
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Isotonic
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Hypertonic
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Solute
Explanation
Correct Answer A: Hypotonic
Explanation of the Correct Answer:
A) Hypotonic
A hypotonic solution has a lower salt (solute) concentration compared to the inside of red blood cells. When red blood cells are placed in a hypotonic solution, water moves into the cells by osmosis due to the higher solute concentration inside the cells. This can cause the cells to swell and potentially burst (hemolysis). Hypotonic solutions are used in medical settings to hydrate cells, especially when there is cellular dehydration.
Explanation of Incorrect Options:
B) Isotonic
Incorrect. An isotonic solution has a salt concentration equal to that of red blood cells. It results in no net movement of water into or out of the cells, so cell size and shape remain stable. Normal saline (0.9% NaCl) is an example of an isotonic solution.
C) Hypertonic
Incorrect. A hypertonic solution has a higher salt concentration than that of red blood cells. In this case, water leaves the cells to move into the extracellular fluid, causing the cells to shrink (crenation).
D) Solute
Incorrect. Solute is a general term for any substance dissolved in a solvent to form a solution. It does not describe the concentration or the type of solution relative to red blood cells.
Summary:
A hypotonic solution contains a lower salt concentration than red blood cells, leading to water movement into the cells. Isotonic and hypertonic solutions either maintain or reduce cell volume, respectively. The term "solute" does not specify the nature of the solution in relation to red blood cells.
Which of the following mediates the body's response to stress
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Cortisol
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Calcitonin
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Thyroid-stimulating hormone
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Growth hormone
Explanation
Correct Answer A: Cortisol
Detailed Explanation of the Correct Answer:
A) Cortisol
This is the correct answer. Cortisol is a hormone produced by the adrenal glands in response to stress. It plays a key role in the body's stress response by increasing blood glucose levels, suppressing the immune system, and aiding in the metabolism of fats, proteins, and carbohydrates. These effects prepare the body to manage stressful situations and are a key part of the body's "fight-or-flight" response.
Explanation of Incorrect Options:
B) Calcitonin
Incorrect. Calcitonin is a hormone produced by the thyroid gland that helps regulate calcium levels in the blood. It does not play a role in the body's response to stress.
C) Thyroid-stimulating hormone (TSH)
Incorrect. TSH is produced by the pituitary gland and stimulates the thyroid gland to produce thyroid hormones (T3 and T4), which regulate metabolism. While thyroid hormones affect the body's energy metabolism, they are not directly involved in the acute response to stress.
D) Growth hormone
Incorrect. Growth hormone is produced by the pituitary gland and is involved in growth, cell repair, and metabolism. While growth hormone has some effects on stress and metabolism, it is not the primary hormone involved in the body’s immediate response to stress.
Summary:
Cortisol is the main hormone responsible for mediating the body's response to stress, by increasing blood glucose levels and preparing the body for stressful situations. The other options—calcitonin, TSH, and growth hormone—are involved in different physiological processes, but not directly in stress response.
Which of the following is an effect of nerve impulses on smooth muscle
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Regulation of heartbeat
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Initiation of gross motor skills
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Involuntary muscle contractions
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Voluntary contraction of muscles
Explanation
Correct Answer C: Involuntary muscle contractions
Detailed Explanation of the Correct Answer:
C) Involuntary muscle contractions
This is the correct answer. Smooth muscle is primarily involved in involuntary functions and is regulated by nerve impulses as part of the autonomic nervous system. These muscle contractions occur without conscious control and are essential for functions such as digestion, blood vessel constriction, and regulating the movement of air in the lungs. The autonomic nervous system (which includes the sympathetic and parasympathetic systems) sends signals to smooth muscles to induce these contractions.
Explanation of Incorrect Options:
A) Regulation of heartbeat
Incorrect. The regulation of heartbeat is primarily controlled by the cardiac muscle, not smooth muscle. While nerve impulses from the autonomic nervous system do influence heart rate and strength of contraction, the heart's rhythmic contractions are driven by specialized pacemaker cells in the heart itself, such as those in the sinoatrial (SA) node.
B) Initiation of gross motor skills
Incorrect. Gross motor skills involve the contraction of skeletal muscle, which is under voluntary control via the somatic nervous system. Smooth muscle does not participate in gross motor activities, which require larger movements such as walking or lifting, driven by skeletal muscles.
D) Voluntary contraction of muscles
Incorrect. Voluntary muscle contractions are controlled by skeletal muscle, not smooth muscle. Skeletal muscle contraction is governed by the somatic nervous system, which enables conscious control over movements. Smooth muscle, in contrast, functions involuntarily, without conscious effort.
Summary:
Smooth muscle contractions are involuntary, controlled by the autonomic nervous system, and help regulate processes like digestion and blood flow. The regulation of heartbeat is linked to cardiac muscle, while gross motor skills and voluntary contractions are functions of skeletal muscle, not smooth muscle.
Which of the following is a major function of the larynx
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Swallowing
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Hiccupping
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Coughing
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Speaking
Explanation
Correct Answer D: Speaking
Detailed Explanation of the Correct Answer:
D. Speaking
The larynx, commonly known as the voice box, is a cartilaginous structure located in the upper part of the trachea. One of its primary functions is phonation (voice production). The larynx contains the vocal cords (vocal folds), which vibrate as air passes through them, producing sound. The pitch and volume of the voice can be modified by changing the tension and position of the vocal cords, as well as the flow of air.
In addition to its role in speaking, the larynx also plays secondary roles in protecting the airway during swallowing and in facilitating breathing, but speech production is its defining function.
Explanation of Incorrect Options:
A. Swallowing
Swallowing is primarily coordinated by the pharynx and the epiglottis. While the larynx elevates during swallowing to help prevent aspiration by closing the epiglottis over the trachea, swallowing is not the main function of the larynx.
B. Hiccupping
Hiccups are caused by involuntary contractions of the diaphragm, followed by the sudden closure of the vocal cords, producing the characteristic "hic" sound. The larynx may be involved in the sound, but hiccupping is not a function of the larynx—it is more of a reflex involving the diaphragm and the phrenic nerve.
C. Coughing
Coughing is a protective reflex that involves several structures, including the larynx, trachea, and lungs, to expel irritants. While the larynx plays a supporting role by closing and then forcefully opening the vocal cords, creating pressure to expel air, coughing is not its primary function.
Summary:
The larynx’s main role is to produce sound for speech by housing and manipulating the vocal cords.
Which of the following is the mucous membrane that lines the inner surface of the eyelid and the anterior surface of the eyeball
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Conjunctiva
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Sclera
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Ciliary body
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Cornea
Explanation
Correct Answer A: Conjunctiva
Detailed Explanation of the Correct Answer:
A. Conjunctiva
The conjunctiva is a thin, transparent mucous membrane that lines the inner surface of the eyelids (palpebral conjunctiva) and extends to cover the anterior surface of the sclera up to the edge of the cornea (bulbar conjunctiva). Its primary function is to protect the eye by producing mucus and tears (in small amounts), keeping the eye lubricated, and serving as a barrier to pathogens and debris. The conjunctiva also contains blood vessels, lymphatics, and immune cells, contributing to ocular defense.
Explanation of Incorrect Options:
B. Sclera
The sclera is the white, fibrous outer layer of the eyeball that provides structural support and protection. It is not a mucous membrane and is not responsible for lining the inner eyelid or anterior eyeball. The conjunctiva overlays part of the sclera but is a separate tissue.
C. Ciliary body
The ciliary body is part of the middle vascular layer (uvea) of the eye. It contains the ciliary muscle, which controls the shape of the lens, and the ciliary processes, which produce aqueous humor. It is located behind the iris and has no role in lining the eyelids or the anterior surface of the eyeball.
D. Cornea
The cornea is the clear, transparent front part of the eye that covers the iris, pupil, and anterior chamber. It is involved in focusing light onto the retina but is not a mucous membrane and does not line the eyelid or the sclera. The conjunctiva stops at the edge of the cornea.
Summary:
The conjunctiva is the correct structure that lines the inside of the eyelid and the anterior surface of the eyeball, playing an important role in eye protection and lubrication.
What characteristic of receptors aids in the selective permeability of the cell membrane
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Receptor sites match the shape of a specific chemical.
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Receptor sites can match a wide range of chemical configurations.
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Receptor sites prevent direct passage of substances.
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Receptor sites permit direct free passage of substances readily across the cell membrane.
Explanation
Correct Answer A: Receptor sites match the shape of a specific chemical.
Detailed Explanation of the Correct Answer:
A. Receptor sites match the shape of a specific chemical.
This describes the lock-and-key model of receptor function. Receptor proteins embedded in the cell membrane are highly specific—they are shaped to bind only to particular molecules (ligands), such as hormones or neurotransmitters. This specificity contributes to the selective permeability of the membrane, as only molecules with the correct structure can interact with these receptors to trigger a response or gain entry into the cell.
This mechanism is critical for cellular communication, transport, and signaling, ensuring that only designated substances influence cellular activity or are allowed entry, maintaining internal homeostasis.
Explanation of Incorrect Options:
B. Receptor sites can match a wide range of chemical configurations.
This is incorrect because receptor sites are highly specific, not broadly receptive. If receptors matched a wide variety of chemicals, it would compromise selectivity, defeating the purpose of selective permeability.
C. Receptor sites prevent direct passage of substances.
While receptor sites don't typically form channels for direct passage, their primary function is not to block substances but to bind specific molecules and sometimes trigger downstream effects like channel opening. Blocking is more associated with the lipid bilayer or other structural features of the membrane.
D. Receptor sites permit direct free passage of substances readily across the cell membrane.
This is incorrect. Receptor sites themselves do not act as open channels. Free passage typically occurs through simple diffusion or open ion channels—not through receptor sites. Receptors facilitate specific interactions but do not allow open access across the membrane.
Summary:
The selective permeability of the cell membrane is aided by the specific shape-matching property of receptor sites. Only molecules with the right shape (ligands) can bind to their corresponding receptors, allowing the cell to regulate which substances influence its function.
Which of the following plasma proteins is synthesized by the liver and contributes to the colloid osmotic pressure of the blood
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Globulin
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Albumin
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Fibrinogen
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Complement
Explanation
Correct Answer B: Albumin
Detailed Explanation of the Correct Answer:
B) Albumin
This is the correct answer. Albumin is a plasma protein synthesized by the liver that plays a crucial role in maintaining the colloid osmotic pressure (also known as oncotic pressure) of the blood. Colloid osmotic pressure helps to regulate the movement of water between the blood and tissues, maintaining proper fluid balance. Albumin is the most abundant plasma protein and its primary function is to keep the fluid in the blood vessels, preventing it from leaking into the tissues.
Explanation of Incorrect Options:
A) Globulin
Incorrect. Globulins are a group of plasma proteins that include antibodies (immunoglobulins) and proteins involved in transport and clotting, but they are not primarily responsible for maintaining colloid osmotic pressure. While globulins play important roles in immunity and transport, they do not have the same osmotic effect as albumin.
C) Fibrinogen
Incorrect. Fibrinogen is a plasma protein involved in blood clotting. It is converted into fibrin during the clotting process, which helps form blood clots to stop bleeding. Fibrinogen does not contribute significantly to colloid osmotic pressure.
D) Complement
Incorrect. The complement system consists of a group of proteins involved in the immune response, particularly in the destruction of pathogens. While complement proteins play a role in immune defense, they do not contribute to colloid osmotic pressure in the blood.
Summary:
Albumin is the plasma protein that is synthesized by the liver and is the primary contributor to colloid osmotic pressure in the blood, helping to maintain fluid balance. Other plasma proteins like globulin, fibrinogen, and complement have different functions related to immunity, clotting, and pathogen defense but do not play a role in osmotic pressure regulation.
Which of the following pairs correctly matches a cellular organelle with its function
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Golgi apparatus - protein synthesis
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Smooth endoplasmic reticulum - energy production
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Cytoskeleton - movement
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Cell membrane - storage
Explanation
Correct Answer C: Cytoskeleton - movement
Detailed Explanation of the Correct Answer:
C) Cytoskeleton - movement
This is the correct answer. The cytoskeleton is a network of protein filaments and tubules within the cytoplasm that provides structural support to the cell. It plays a crucial role in cellular movement, both within the cell and as a whole. The cytoskeleton is involved in processes such as cell division, cell shape maintenance, and intracellular transport of organelles and vesicles. It also facilitates the movement of the entire cell, like in amoeboid movement or ciliary action.
Explanation of Incorrect Options:
A) Golgi apparatus - protein synthesis
Incorrect. The Golgi apparatus is not directly involved in protein synthesis. Its primary function is to modify, sort, and package proteins and lipids that are synthesized by the endoplasmic reticulum (ER), preparing them for transport to their final destinations (either within or outside the cell). Protein synthesis primarily takes place in ribosomes and on the rough endoplasmic reticulum (ER).
B) Smooth endoplasmic reticulum - energy production
Incorrect. The smooth endoplasmic reticulum (ER) is involved in the synthesis of lipids, detoxification of drugs and toxins, and metabolism of carbohydrates. It does not play a primary role in energy production. Energy production occurs in the mitochondria, where cellular respiration takes place to generate ATP.
D) Cell membrane - storage
Incorrect. The cell membrane serves as a barrier that separates the internal environment of the cell from the external environment and regulates the movement of substances in and out of the cell. It is not involved in storage. Storage of substances, such as nutrients or waste products, occurs in structures like vacuoles or lysosomes.
Summary:
The cytoskeleton is correctly matched with movement as it plays a critical role in cellular shape, intracellular transport, and motility. The other organelles are either misattributed to functions they do not primarily perform or are involved in different cellular processes.
Which of the following cells is involved in mineral resorption from bone
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Osteoclasts
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Osteoblasts
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Canaliculi
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Osteon
Explanation
Correct Answer A: Osteoclasts
Detailed Explanation of the Correct Answer:
A) Osteoclasts
This is the correct answer. Osteoclasts are specialized cells that break down bone tissue during the process of bone resorption. They secrete enzymes and acid that dissolve the mineralized bone matrix, releasing calcium, phosphate, and other minerals into the bloodstream. This process is crucial for maintaining the balance of minerals in the body and is part of bone remodeling, where old bone tissue is replaced with new tissue. Osteoclasts play a critical role in regulating mineral levels, especially calcium, in the body.
Explanation of Incorrect Options:
B) Osteoblasts
Incorrect. Osteoblasts are responsible for the formation of new bone tissue. They synthesize and secrete the components of the bone matrix (such as collagen) and are involved in the process of bone mineralization. While osteoblasts build bone, they do not resorb minerals from bone.
C) Canaliculi
Incorrect. Canaliculi are small channels or ducts within the bone that connect osteocytes (mature bone cells) to one another. They allow for the exchange of nutrients and waste products between osteocytes and the blood supply. Canaliculi are involved in cell communication but are not responsible for resorbing minerals from bone.
D) Osteon
Incorrect. An osteon, also known as a Haversian system, is the structural unit of compact bone. It consists of concentric layers of bone matrix around a central canal that contains blood vessels and nerves. The osteon provides structural support but is not involved in mineral resorption.
Summary:
Osteoclasts are the cells responsible for mineral resorption from bone. They break down bone tissue, releasing minerals like calcium into the bloodstream. In contrast, osteoblasts form new bone, canaliculi enable communication between osteocytes, and osteons are structural units of bone tissue.
Which of the following actions is controlled by the autonomic nervous system
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Walking
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Chewing
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Heart beating
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Talking
Explanation
Correct Answer C: Heart beating
Detailed Explanation of the Correct Answer:
C) Heart beating
This is the correct answer. The autonomic nervous system (ANS) controls involuntary body functions, including the regulation of the heart rate, digestion, respiratory rate, pupil dilation, and glandular secretions. The heart beating is primarily regulated by the sympathetic and parasympathetic divisions of the ANS. The sympathetic nervous system increases heart rate during stress or physical activity, while the parasympathetic system decreases it during rest. This automatic, involuntary control of cardiac function is a hallmark of autonomic regulation.
Explanation of Incorrect Options:
A) Walking
Incorrect. Walking is a voluntary movement controlled by the somatic nervous system, which governs actions under conscious control. Although balance and coordination involve complex neural integration, the decision and initiation to walk are conscious processes.
B) Chewing
Incorrect. Chewing is also a voluntary action, initiated and controlled by the somatic nervous system. Although some reflexive aspects (like adjusting bite pressure) may involve subconscious feedback, the primary control is voluntary.
D) Talking
Incorrect. Talking involves the use of skeletal muscles for articulation, controlled by the somatic nervous system. It is a conscious, voluntary action that engages motor areas of the brain responsible for speech.
Summary:
The autonomic nervous system controls involuntary physiological functions, and heart beating is one of its primary responsibilities. In contrast, walking, chewing, and talking are voluntary actions regulated by the somatic nervous system.
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