NUR 123 Exam #2 Fall 2025

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Ace Your Test with NUR 123 Exam #2 Fall 2025 Actual Questions and Solutions - Full Set

Free NUR 123 Exam #2 Fall 2025 Questions

1.

The nurse caring for a patient prescribed the antimetabolite methotrexate would monitor which labs? Select all that apply.

  • A. Platelets
  • B. TSH
  • C. White blood cells
  • D. LFTs
  • E. Creatinine

Explanation

Explanation
Correct Answer:
A. Platelets
C. White blood cells
D. LFTs
E. Creatinine

Explanation

A. Platelets
Methotrexate, an antimetabolite used for various conditions like cancer and autoimmune diseases, can cause bone marrow suppression. This results in a decrease in platelets, which can lead to an increased risk of bleeding. Monitoring platelet levels helps ensure early detection of thrombocytopenia, a possible side effect of methotrexate therapy.

C. White blood cells
Methotrexate can also cause leukopenia, a reduction in white blood cells, which increases the risk of infections. Monitoring WBC counts is crucial to detect any early signs of bone marrow suppression that could result in an increased vulnerability to infections.

D. LFTs
Methotrexate can be hepatotoxic, so liver function tests (LFTs) are important to monitor for any signs of liver damage, such as elevated ALT, AST, or bilirubin. Regular monitoring of LFTs ensures that any hepatic issues are caught early and the dosage can be adjusted if necessary.

E. Creatinine
Methotrexate is excreted through the kidneys, and renal toxicity can occur, particularly with high doses. Monitoring creatinine levels is essential to assess kidney function and prevent nephrotoxicity, especially in patients with pre-existing renal conditions.

2.

What drug is used to reverse muscle paralysis caused by pancuronium?

  • A. Neostigmine
  • B. Dantrolene
  • C. Flumazenil
  • D. Midazolam

Explanation

Explanation
Correct Answer:
A. Neostigmine

Explanation:
Neostigmine is used to reverse muscle paralysis caused by non-depolarizing neuromuscular blockers such as pancuronium. It works by inhibiting acetylcholinesterase, which allows acetylcholine to accumulate at the neuromuscular junction, thereby stimulating muscle contraction.

3.

The nurse recognizes that the antimetabolite drug, methotrexate, is contraindicated in which patient condition?

  • A. Pregnancy
  • B. Mucositis
  • C. Cardiac dysrhythmias
  • D. Brain cancer

Explanation

Explanation
Correct Answer:
A. Pregnancy

Explanation:
Methotrexate is a potent antimetabolite used in cancer treatment and autoimmune conditions. However, it is contraindicated during pregnancy because it is classified as a teratogen. Methotrexate can cause severe birth defects and fetal harm by interfering with the development of the fetus. Therefore, it should not be used by pregnant women, and adequate contraception should be used during treatment. If pregnancy occurs, methotrexate should be discontinued immediately due to its potential risks to fetal development.

4.

A patient has been prescribed enfuvirtide, a Fusion Inhibitor, to treat Human Immunodeficiency Virus (HIV). What adverse reaction will the nurse monitor the patient for?

  • A. Hypertension
  • B. Bleeding
  • C. Localized erythema
  • D. Dizziness

Explanation

Explanation
Correct Answer:
C. Localized erythema

Explanation

C. Localized erythema
Enfuvirtide is a fusion inhibitor used in the treatment of HIV. One of the most common side effects of enfuvirtide is localized erythema (redness) at the injection site. This reaction occurs due to the subcutaneous injection of the drug and is often associated with mild irritation or inflammation. Nurses should monitor the injection site for signs of erythema, swelling, or pain, as well as any signs of infection.

5.

A nurse is caring for a patient who is taking ritonavir, a protease inhibitor, to treat Human Immunodeficiency Virus (HIV). Which adverse effect of this drug will the nurse monitor the patient for?

  • A. Increased TSH level
  • B. Decreased ALT level
  • C. Hypercalcemia
  • D. Hyperglycemia

Explanation

Explanation
Correct Answer:
D. Hyperglycemia

Explanation

D. Hyperglycemia
Ritonavir, a protease inhibitor used in the treatment of HIV, is known to cause hyperglycemia as a common side effect. Protease inhibitors, including ritonavir, can impair insulin sensitivity and promote insulin resistance, leading to elevated blood glucose levels. The nurse should monitor blood glucose levels regularly and be alert for symptoms of hyperglycemia, such as increased thirst, frequent urination, and fatigue. Long-term use of ritonavir may increase the risk of developing diabetes in some patients.

6.

A nurse is caring for a patient taking maraviroc. Which statement describes how this CCR5 antagonist fights Human Immunodeficiency Virus (HIV)?

  • A. Maraviroc prevents the reproduction of viral DNA and therefore interrupts the cell replication
  • B. Maraviroc prevents HIV from entering your cells by binding to a cysteine chemokine receptor on the cell membrane
  • C. Maraviroc inhibits enzymes and prevents the reproduction of viral DNA preventing cell entry and reproduction of the cell.
  • D. Maraviroc inhibits enzymes needed for HIV replication

Explanation

Explanation
Correct Answer:
B. Maraviroc prevents HIV from entering your cells by binding to a cysteine chemokine receptor on the cell membrane

Explanation:
Maraviroc is a CCR5 antagonist that works by blocking the CCR5 receptor on the surface of T-cells. The CCR5 receptor is one of the co-receptors that HIV uses to enter the host cell. By binding to this receptor, maraviroc prevents HIV from entering the cells and infecting them, thereby reducing the viral load. It does not affect viral DNA replication directly, unlike other antiretroviral agents that target viral enzymes.

7.

The nurse is teaching a patient who is newly diagnosed with type I diabetes mellitus about insulin administration. Which statement by the patient indicates a need for further teaching?

  • A. "I should give each injection approximately two finger widths away from a previous injection."
  • B. "I will not be concerned about a raised lump under my skin from injecting insulin."
  • C. "Insulin is absorbed better from subcutaneous sites on my abdomen."
  • D. "I will rotate the site of each injection."

Explanation

Explanation
Correct Answer:
B. "I will not be concerned about a raised lump under my skin from injecting insulin."

Explanation:
A raised lump or hardened area under the skin, known as lipohypertrophy, can occur from repeated insulin injections in the same area. Over time, this can interfere with insulin absorption and lead to erratic blood sugar control. Patients should be instructed to avoid injecting into these areas and should rotate injection sites to prevent this complication. If the patient is not concerned about the lumps, further teaching is needed to emphasize the importance of site rotation and monitoring for lipohypertrophy.

8.

A patient is ordered to receive regular insulin at mealtimes. The nurse will instruct this patient to administer the medication at which time?

  • A. 15 minutes after eating
  • B. 30 minutes before eating
  • C. 10 minutes after eating
  • D. 5 minutes before eating

Explanation

Explanation
Correct Answer:
D. 5 minutes before eating

Explanation

D. 5 minutes before eating
Regular insulin, a short-acting insulin, typically starts working within 30 minutes of injection and peaks around 2 to 3 hours. To ensure that insulin is active when blood sugar rises after eating, it should be administered approximately 30 minutes before meals. However, it is most effective when injected 5 to 15 minutes prior to the meal to match the onset of action with the increase in blood glucose after eating.

9.

What is the reversal drug for the over-sedative effects of benzodiazepines?

  • A. Midazolam
  • B. Flumazenil
  • C. Dantrolene
  • D. Neostigmine

Explanation

Explanation
Correct Answer:
B. Flumazenil

Explanation:
Flumazenil is a benzodiazepine antagonist used to reverse the sedative effects of benzodiazepines. It works by competitively inhibiting the action of benzodiazepines at their receptor sites in the central nervous system.

10.

Education for the nurse caring for the patient receiving the hormonal agent leuprolide would include which instructions?

  • A. The drug may cause hot flashes, erectile dysfunction, and decreased libido.
  • B. Vaginal bleeding may occur.
  • C. An increased dose of warfarin will be necessary.
  • D. Liver function tests must be assessed weekly.

Explanation

Explanation
Correct Answer:
A. The drug may cause hot flashes, erectile dysfunction, and decreased libido.

Explanation:
Leuprolide is a GnRH agonist used in the treatment of hormone-sensitive cancers such as prostate cancer and endometriosis. It works by suppressing the production of sex hormones, which can lead to symptoms such as hot flashes, erectile dysfunction, and decreased libido. These side effects are commonly associated with the drug’s mechanism of action in reducing testosterone levels in men and estrogen levels in women. The nurse should inform patients of these potential effects to ensure they are prepared and can manage them effectively.

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